GNDC is the first database dedicated to capturing gene-encoded natural diverse components—including metabolites, nucleic acids, peptides, and carbohydrates—sourced from traditional medicines. By integrating a vast "billion-scale" repertoire of natural compounds, it provides an expansive "chemical space" for drug discovery. This resource facilitates the identification of novel bioactive molecules that could serve as leads in pharmaceutical research.

Moreover, GNDC establishes critical connections between genomic data, compound characteristics, and functional insights, driving the evolution of drug discovery from an experience-based approach to a data-driven research and development paradigm. Its comprehensive dataset supports advanced analytics and machine learning applications, enhancing the precision and efficiency of new drug development processes.